Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan, Republic of China.
J Nat Prod. 2009 Mar 27;72(3):465-8. doi: 10.1021/np800362g.
Chemical investigation of the octocoral Sarcophyton ehrenbergi, collected at the Dongsha Islands, Taiwan, has led to the isolation of a known ceramide (1) and two new cerebrosides, sarcoehrenosides A (2) and B (4), along with three known cerebrosides (3, 5, and 6). The structures of the new compounds were established by spectroscopic and chemical methods. Sarcoehrenoside A (2) differs from previously known marine cerebrosides in that it possesses a rare alpha-glucose moiety. Compounds 1-6 were evaluated for antimicrobial activity against a small panel of bacteria and for anti-inflammatory activity using RAW 264.7 macrophages.
从台湾东沙群岛采集的柳珊瑚 Sarcophyton ehrenbergi 中进行的化学研究，导致分离出一种已知的神经酰胺（1）和两种新的脑苷脂，sarcoehrenosides A（2）和 B（4），以及三种已知的脑苷脂（3、5 和 6）。新化合物的结构通过光谱和化学方法确定。Sarcoehrenoside A（2）与先前已知的海洋脑苷脂不同，因为它具有罕见的α-葡萄糖部分。对化合物 1-6 进行了抗菌活性评估，对一小部分细菌进行了评估，并使用 RAW 264.7 巨噬细胞进行了抗炎活性评估。
