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孕期维生素D摄入量:与母亲特征及婴儿出生体重的关联

Vitamin D intake during pregnancy: association with maternal characteristics and infant birth weight.

作者信息

Scholl Theresa O, Chen Xinhua

机构信息

Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey-SOM, Stratford, New Jersey, USA.

出版信息

Early Hum Dev. 2009 Apr;85(4):231-4. doi: 10.1016/j.earlhumdev.2008.10.006. Epub 2008 Nov 12.

Abstract

BACKGROUND

Vitamin D insufficiency is beginning to be recognized as a public health problem. It is plausible that some portion of the lower Vitamin D levels which characterize minority populations is related to diet.

AIMS

We examined and described total Vitamin D intake during pregnancy from the mean of three 24-hour recalls plus use of dietary supplements.

STUDY DESIGN

Prospective cohort.

SUBJECTS

2251 low income, minority gravidae from Camden, New Jersey, USA.

OUTCOME MEASURES

Differences in total Vitamin D intake by maternal ethnicity. BMI and other factors (age, parity) and associations of total Vitamin D intake with gestation duration and birth weight adjusted for gestation.

RESULTS AND CONCLUSIONS

Total Vitamin D intake was significantly lower for minority gravidae (African American, and Hispanic, mainly Puerto Rican), for parous women, and for women with pregravid BMIs consistent with obesity or being overweight. After control for energy, other nutrients, and other potential confounding variables, total intake of Vitamin D was associated with increased infant birth weight; gravidae below the current adequate intake (<5 microg/day or 200 IU) had infants with significantly lower birth weights (p<0.05). Additional intake of Vitamin D may be of importance since higher intake is associated with increased birth weight in a population at risk of adverse pregnancy outcomes.

摘要

背景

维生素D缺乏正开始被视为一个公共卫生问题。少数族裔人群维生素D水平较低的部分原因可能与饮食有关,这是有道理的。

目的

我们通过三次24小时回忆的平均值加上膳食补充剂的使用情况,对孕期维生素D的总摄入量进行了检查和描述。

研究设计

前瞻性队列研究。

研究对象

来自美国新泽西州卡姆登的2251名低收入少数族裔孕妇。

观察指标

按母亲种族、体重指数(BMI)及其他因素(年龄、产次)划分的维生素D总摄入量差异,以及维生素D总摄入量与妊娠持续时间和经妊娠调整后的出生体重之间的关联。

结果与结论

少数族裔孕妇(非裔美国人和西班牙裔,主要是波多黎各人)、经产妇以及孕前BMI符合肥胖或超重标准的孕妇,其维生素D总摄入量显著较低。在控制了能量、其他营养素及其他潜在混杂变量后,维生素D的总摄入量与婴儿出生体重增加有关;维生素D摄入量低于当前适宜摄入量(<5微克/天或200国际单位)的孕妇所生婴儿出生体重显著较低(p<0.05)。额外补充维生素D可能很重要,因为在有不良妊娠结局风险的人群中,较高的摄入量与出生体重增加有关。

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