肾癌的流行病学
Epidemiology of kidney cancer.
作者信息
Pascual D, Borque A
机构信息
Department of Urology, San Pedro Hospital, 26006 Logroño, Spain.
出版信息
Adv Urol. 2008;2008:782381. doi: 10.1155/2008/782381. Epub 2008 Nov 4.
Abstract
Some tumors are known to have a definite cause-effect etiology, but renal cell carcinoma (RCC) is not one of them precisely. With regard to RCC we can only try to identify some clinical and occupational factors as well as substances related to tumorigenesis. Smoking, chemical carcinogens like asbestos or organic solvents are some of these factors that increase the risk of the RCC. Viral infections and radiation therapy have also been described as risk factors. Some drugs can increase the incidence of RCC as well as other neoplasms. Of course, genetics plays an outstanding role in the development of some cases of kidney cancer. Chronic renal failure, hypertension, and dialysis need to be considered as special situations. Diet, obesity, lifestyle, and habits can also increase the risk of RCC. The aim of this review is to summarize the well-defined causes of renal cell carcinoma.
摘要
已知一些肿瘤具有明确的因果病因，但肾细胞癌（RCC）确切来说并非如此。关于肾细胞癌，我们只能尝试识别一些临床和职业因素以及与肿瘤发生相关的物质。吸烟、石棉或有机溶剂等化学致癌物是增加肾细胞癌风险的一些因素。病毒感染和放射治疗也被描述为风险因素。一些药物会增加肾细胞癌以及其他肿瘤的发病率。当然，遗传学在某些肾癌病例的发展中起着突出作用。慢性肾衰竭、高血压和透析需要被视为特殊情况。饮食、肥胖、生活方式和习惯也会增加肾细胞癌的风险。本综述的目的是总结肾细胞癌明确的病因。
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