Jeong Jeong-Jo, Choi Myung-Gyu, Cho Young-Seok, Lee Seung-Geun, Oh Jung-Hwan, Park Jae-Myung, Cho Yu-Kyung, Lee In-Seok, Kim Sang-Woo, Han Sok-Won, Choi Kyu-Yong, Chung In-Sik
Division of Gastroenterology, Department of Internal Medicine, Kangnam St. Mary's Hospital, The Catholic University of Korea, #137-040, 505, Banpo-Dong, Seocho-Gu, Seoul 137-040, South Korea.
World J Gastroenterol. 2008 Nov 7;14(41):6388-94. doi: 10.3748/wjg.14.6388.
To evaluate the prevalence of chronic gastrointestinal symptoms and their impact on health-related quality of life (HRQOL) in the Korean population.
A cross-sectional survey, using a reliable and valid Rome II based questionnaire, was performed on randomly selected residents, between 18 and 69 years in age. All respondents were interviewed at their homes or offices by a team of interviewers. The impact of chronic gastrointestinal symptoms on HRQOL was assessed using the Korean version of the 36-item Short-Form general health survey (SF-36).
Of the 1807 eligible subjects, 1417 (78.4%: male 762; female 655) were surveyed. Out of the respondents, 18.6% exhibited at least one chronic gastrointestinal symptom. The prevalence of gastroesophageal reflux disease (GERD), defined as heartburn and/or acid regurgitation experienced at least weekly, was 3.5% (95% CI, 2.6-4.5). The prevalence of uninvestigated dyspepsia, irritable bowel syndrome (IBS) and chronic constipation based on Rome II criteria were 11.7% (95% CI, 10.1-13.5), 2.2% (95% CI, 1.5-3.1), and 2.6% (95% CI, 1.8-3.5) respectively. Compared with subjects without chronic gastrointestinal symptoms (n=1153), those with GERD (n=50), uninvestigated dyspepsia (n=166) and IBS (n=31) had significantly worse scores on most domains of the SF-36 scales.
The prevalence of GERD, uninvestigated dyspepsia and IBS were 3.5%, 11.7% and 2.2% respectively, in the Korean population. The health-related quality of life was significantly impaired in subjects with GERD, uninvestigated dyspepsia and IBS in this community.
评估韩国人群中慢性胃肠道症状的患病率及其对健康相关生活质量（HRQOL）的影响。
采用基于罗马II标准的可靠有效问卷，对18至69岁随机选取的居民进行横断面调查。所有受访者均由一组访员在其家中或办公室进行访谈。使用韩国版36项简短健康调查问卷（SF-36）评估慢性胃肠道症状对HRQOL的影响。
在1807名符合条件的受试者中，1417名（78.4%：男性762名；女性655名）接受了调查。在受访者中，18.6%表现出至少一种慢性胃肠道症状。胃食管反流病（GERD）的患病率，定义为至少每周出现一次烧心和/或反酸，为3.5%（95%可信区间，2.6-4.5）。基于罗马II标准的未确诊消化不良、肠易激综合征（IBS）和慢性便秘的患病率分别为11.7%（95%可信区间，10.1-13.5）、2.2%（95%可信区间，1.5-3.1）和2.6%（95%可信区间，1.8-3.5）。与无慢性胃肠道症状的受试者（n=1153）相比，患有GERD（n=50）、未确诊消化不良（n=166）和IBS（n=31）的受试者在SF-36量表的大多数领域得分明显更低。
韩国人群中GERD、未确诊消化不良和IBS的患病率分别为3.5%、11.7%和2.2%。在该社区中，患有GERD、未确诊消化不良和IBS的受试者的健康相关生活质量明显受损。
