纳基基醌E和F，源自海洋海绵的新型二聚倍半萜醌。

Nakijiquinones E and F, new dimeric sesquiterpenoid quinones from marine sponge.

作者信息

Takahashi Yohei, Kubota Takaaki, Kobayashi Jun'ichi

机构信息

Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.

出版信息

Bioorg Med Chem. 2009 Mar 15;17(6):2185-8. doi: 10.1016/j.bmc.2008.10.080. Epub 2008 Nov 5.

DOI:10.1016/j.bmc.2008.10.080

PMID:19017563

Abstract

Two new dimeric sesquiterpenoid quinones, nakijiquinones E (1) and F (2), have been isolated from an Okinawan marine sponge, and the structures and relative stereochemistry of 1 and 2 were elucidated on the basis of the spectral data. Nakijiquinones E (1) and F (2) were the first dimeric sesquiterpenoid quinones possessing a 3-aminobenzoate moiety.

摘要

从冲绳海洋海绵中分离出了两种新的二聚倍半萜醌类化合物，即仲红海绵醌E（1）和仲红海绵醌F（2），并根据光谱数据阐明了1和2的结构及相对立体化学。仲红海绵醌E（1）和仲红海绵醌F（2）是首次发现的含有3-氨基苯甲酸酯部分的二聚倍半萜醌类化合物。