Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
J Nat Prod. 2010 Mar 26;73(3):467-71. doi: 10.1021/np900470e.
Nine new sesquiterpenoid quinones, nakijiquinones J-R (1-9), have been isolated from three collections of Okinawan marine sponges of the family Spongiidae, and the structures and configurations were elucidated from the spectroscopic data and chemical correlations. Nakijiquinones J-L (1-3), M and N (4 and 5, respectively), O (6), P and Q (7 and 8, respectively), and R (9) are new sesquiterpenoid quinones possessing (S)-2-methylbutylamine, isopentylamine, isobutylamine, phenethylamine, and taurine residues, respectively, attached to each quinone ring.
从三种 Spongiidae 科的冲绳海洋海绵中分离得到了 9 种新的倍半萜醌类化合物，nakijiquinones J-R（1-9），并通过光谱数据和化学关联阐明了它们的结构和构型。nakijiquinones J-L（1-3）、M 和 N（4 和 5，分别）、O（6）、P 和 Q（7 和 8，分别）和 R（9）是新的倍半萜醌类化合物，分别具有（S）-2-甲基丁基胺、异戊基胺、异丁基胺、苯乙胺和牛磺酸残基，分别连接到每个醌环上。
