Mizyed I, Fass S S, Fass R
Department of Medicine, Southern Arizona VA Health Care System and University of Arizona Health Sciences Center, Tucson, AZ 85723-0001, USA.
Aliment Pharmacol Ther. 2009 Feb 15;29(4):351-8. doi: 10.1111/j.1365-2036.2008.03883.x. Epub 2008 Nov 8.
A growing number of studies have shown the impact of psychological comorbidities on gastro-oesophageal reflux disease (GERD) patients' symptom reports and healthcare-seeking behaviour.
To review the reported relationship between GERD and psychological comorbidity.
Review of the literature on GERD and psychological comorbidity.
Psychological comorbidity is common among GERD patients and appears to afflict all GERD phenotypes. Sexual and physical abuse is also common in GERD patients. Stress enhances perception of oesophageal acid exposure. Treatment for GERD, especially in those who are not responsive to antireflux treatment, may require further evaluation for psychological comorbidity.
Psychological comorbidity is very common in GERD patients and is likely to play an important role in response, or failure of response, to proton pump inhibitor treatment.
越来越多的研究表明心理合并症对胃食管反流病（GERD）患者的症状报告及就医行为产生影响。
综述已报道的GERD与心理合并症之间的关系。
回顾关于GERD与心理合并症的文献。
心理合并症在GERD患者中很常见，似乎影响所有GERD表型。性虐待和身体虐待在GERD患者中也很常见。压力会增强对食管酸暴露的感知。GERD的治疗，尤其是对抗反流治疗无反应者，可能需要进一步评估心理合并症。
心理合并症在GERD患者中非常常见，并且可能在质子泵抑制剂治疗的反应或无反应中起重要作用。
