Melanson Kathleen J, Angelopoulos Theodore J, Nguyen Von, Zukley Linda, Lowndes Joshua, Rippe James M
Rippe Lifestyle Institute, Shrewsbury, MA 01545, USA.
Am J Clin Nutr. 2008 Dec;88(6):1738S-1744S. doi: 10.3945/ajcn.2008.25825E.
High-fructose corn syrup (HFCS) has been implicated in excess weight gain through mechanisms seen in some acute feeding studies and by virtue of its abundance in the food supply during years of increasing obesity. Compared with pure glucose, fructose is thought to be associated with insufficient secretion of insulin and leptin and suppression of ghrelin. However, when HFCS is compared with sucrose, the more commonly consumed sweetener, such differences are not apparent, and appetite and energy intake do not differ in the short-term. Longer-term studies on connections between HFCS, potential mechanisms, and body weight have not been conducted. The main objective of this review was to examine collective data on associations between consumption of HFCS and energy balance, with particular focus on energy intake and its regulation.
高果糖玉米糖浆（HFCS）通过一些急性喂养研究中观察到的机制以及在肥胖率上升的那些年里它在食物供应中的高含量，被认为与体重过度增加有关。与纯葡萄糖相比，果糖被认为与胰岛素和瘦素分泌不足以及胃饥饿素抑制有关。然而，当将HFCS与更常食用的甜味剂蔗糖进行比较时，这些差异并不明显，并且短期内食欲和能量摄入没有差异。尚未开展关于HFCS、潜在机制与体重之间联系的长期研究。本综述的主要目的是研究关于HFCS消费与能量平衡之间关联的汇总数据，特别关注能量摄入及其调节。
