Gucciardo L, Lories R, Ochsenbein-Kölble N, Done' E, Zwijsen A, Deprest J
Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, Leuven, Belgium.
BJOG. 2009 Jan;116(2):166-72. doi: 10.1111/j.1471-0528.2008.02005.x.
The fetus is a source of nonembryonic stem cells (SC), with potential applications in perinatal medicine. Cells derived from the placenta, membranes, amniotic fluid or fetal tissues are higher in number, expansion potential and differentiation abilities compared with SC from adult tissues. Although some obstacles keep SC biology at distance from clinical application, the feasibility of using (homologous) SC for tissue engineering for the fetus with a congenital birth defect has been demonstrated. Also, other pathologies may benefit from SC technology.
胎儿是非胚胎干细胞的来源，在围产期医学中有潜在应用价值。与成体组织来源的干细胞相比，来自胎盘、胎膜、羊水或胎儿组织的细胞数量更多、增殖潜力更大且分化能力更强。尽管一些障碍使干细胞生物学与临床应用仍有距离，但已证明使用（同源）干细胞对患有先天性出生缺陷的胎儿进行组织工程的可行性。此外，其他病症也可能从干细胞技术中受益。
