Kakoli Payman, Nandakumar Renu, Romberg Elaine, Arola Dwayne, Fouad Ashraf F
Department of Endodontics, Prosthodontics and Operative Dentistry, Dental School, University of Maryland Baltimore, Baltimore, Maryland 21201, USA.
J Endod. 2009 Jan;35(1):78-81. doi: 10.1016/j.joen.2008.10.004.
The aim of this study was to determine the effects of patient's age on the prevalence and depth of bacterial penetration inside dentinal tubules. Fifty-six single-rooted teeth were divided in two groups based on the patient's age: young (ages 18-25) and old (age >or=60). Teeth were instrumented and inoculated with a standardized bacterial load and incubated for 20 days. Histological analysis was performed to determine the degree of infection of the dentinal tubules by counting the number of invaded tubules and the depth of penetration of bacteria inside the tubules. A significantly higher number of tubules were invaded by bacteria in the young group compared with the old group (p = 0.014). Also, the depth of invasion by bacteria was significantly higher in the young than in the old group (p = 0.033). These results suggest that bacterial infection of dentinal tubules occur to a lesser extent in older patients.
本研究的目的是确定患者年龄对牙本质小管内细菌侵入的发生率和深度的影响。根据患者年龄，将56颗单根牙分为两组：年轻组（18 - 25岁）和老年组（年龄≥60岁）。对牙齿进行预备并接种标准化细菌量，然后孵育20天。通过计数侵入小管的数量和细菌在小管内的侵入深度进行组织学分析，以确定牙本质小管的感染程度。与老年组相比，年轻组中被细菌侵入的小管数量显著更多（p = 0.014）。此外，细菌侵入的深度在年轻组中也显著高于老年组（p = 0.033）。这些结果表明，老年患者牙本质小管的细菌感染程度较低。
