LaKind Judy S, Berlin Cheston M, Mattison Donald R
LaKind Associates, LLC, Catonsville, Maryland, USA.
Breastfeed Med. 2008 Dec;3(4):251-9. doi: 10.1089/bfm.2008.0121.
Abstract The increasing number of environmental chemicals measured in breastmilk is a consequence of improved analytical capabilities and the increased interest in biomonitoring. It has been generally concluded that the benefits to the infant from breastfeeding outweigh potential risks associated with environmental chemical exposures associated with breastfeeding. However, there have been reports of subtle effects on infants associated with chemicals in breastmilk. Associations between concentrations of chemicals in breastmilk and a biochemical or other change in infants may signal the need for further study or regulatory action, whereas on an individual level, these changes may not be considered adverse. For healthcare providers, this distinction is critical, as many in the field are being asked for nuanced information on risks and benefits associated with breastfeeding, and this information is not readily available. Recognizing the challenge faced by healthcare providers, we have explored and developed a case study on dioxins in breastmilk. The essential conclusion for healthcare providers and new parents is that in studies of breastfed versus formula-fed infants across time, including times when levels of environmental chemicals such as dioxins were higher, beneficial effects associated with breastfeeding have been found. The current evidence does not support altering the World Health Organization recommendations promoting and supporting breastfeeding.
摘要 母乳中检测出的环境化学物质数量不断增加，这是分析能力提高以及对生物监测兴趣增加的结果。人们普遍得出结论，母乳喂养对婴儿的益处超过了与母乳喂养相关的环境化学物质暴露带来的潜在风险。然而，已有报告称母乳中的化学物质会对婴儿产生微妙影响。母乳中化学物质浓度与婴儿生化或其他变化之间的关联可能表明需要进一步研究或采取监管行动，而在个体层面，这些变化可能不被视为有害。对于医疗保健提供者而言，这种区分至关重要，因为该领域的许多人都被要求提供有关母乳喂养相关风险和益处的细致信息，而此类信息并不容易获取。认识到医疗保健提供者面临的挑战，我们探索并开展了一项关于母乳中二恶英的案例研究。对于医疗保健提供者和新父母而言，基本结论是，在对母乳喂养婴儿和配方奶喂养婴儿进行的长期研究中，包括二恶英等环境化学物质水平较高的时期，都发现了母乳喂养的有益效果。目前的证据不支持改变世界卫生组织促进和支持母乳喂养的建议。
