青蒿素的未来：天然的、合成的还是重组的？
The future of artemisinins: natural, synthetic or recombinant?
作者信息
Hommel Marcel
机构信息
Institut Pasteur, 25-28 rue du Dr Roux, Paris 75724 Cedex 15, France.
出版信息
J Biol. 2008 Dec 15;7(10):38. doi: 10.1186/jbiol101.
Abstract
Artemisinins are the most important anti-malarial drugs in use today, but are more costly than previous anti-malarials and production and price tend to fluctuate. Alternative ways of producing artemisinins are discussed here in the light of a recent paper in BMC Biotechnology on improving the yield of the precursor, artemisinic acid, in genetically engineered yeast.
摘要
青蒿素是目前使用的最重要的抗疟药物，但比以往的抗疟药物成本更高，而且产量和价格往往波动较大。本文根据《BMC生物技术》上最近一篇关于提高转基因酵母中前体青蒿酸产量的论文，讨论了生产青蒿素的替代方法。
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