Tandon B N, Irshad M, Acharya S K, Joshi Y K
Department of Gastroenterology, All-India Institute of Medical Sciences, New Delhi.
Gastroenterol Jpn. 1991 Jul;26 Suppl 3:192-5. doi: 10.1007/BF02779297.
The present study describes the status of hepatitis C virus infection in 167 patients with severe forms of liver diseases in India. The anti-HCV positivity rate was recorded as 43%, 47%, and 42% in patients with FHF, SAHF, and CAH respectively. HBV and HCV coinfection was recorded in 28% of FHF, 43% of SAHF and 75% of the CAH cases. Superinfection of HCV in HBsAg carriers was recorded in the 54% cases of FHF, 60% of SAHF and 42% of the CAH. None of these 167 patients was positive of HAV-IgM. Further, 27.7% of FHF, 26.4% of SAHF and 15.2% of CAH cases were neither HBV nor HCV markers positive. These can be labelled as non-A, non-B and non-C infections.
本研究描述了印度167例重症肝病患者的丙型肝炎病毒感染状况。在暴发性肝衰竭（FHF）、慢加急性肝衰竭（SAHF）和慢性活动性肝炎（CAH）患者中，抗-HCV阳性率分别记录为43%、47%和42%。FHF患者中28%、SAHF患者中43%以及CAH患者中75%存在HBV和HCV合并感染。HBsAg携带者中HCV重叠感染在FHF病例中占54%，SAHF中占60%，CAH中占42%。这167例患者中无一例HAV-IgM呈阳性。此外，FHF病例中27.7%、SAHF病例中26.4%以及CAH病例中15.2%既无HBV也无HCV标志物呈阳性。这些可被标记为非甲、非乙、非丙型感染。
