Sasada Shinsuke, Ikeda Yoichi, Saitsu Hideki, Saku Motonori
Department of Surgery and Clinical Research Institute, National Hospital Organization Kyushu Medical Center, 1-8-1 Jigyohama Chuo-ku, Fukuoka, 810-8563 Japan.
Hepatogastroenterology. 2008 Sep-Oct;55(86-87):1931-4.
BACKGROUND/AIMS: The number of elderly gastric cancer patients undergoing surgery is rapidly increasing because of the current aging society. To determine an effective surgical treatment method, the clinicopathological characteristics of such patients should therefore be clarified.
Between 1979 and 2005, 2010 patients with gastric cancer underwent curative surgery in our institute. Clinicopathological characteristics of 109 patients in the elderly group (> or = 80-years-old) were compared with those of 1901 patients in the young group (< 80-years-old).
In the elderly group, cancers of the lower third of the stomach and differentiated types, and less-invasive surgery were common. The 5-year survival rate specific to gastric cancer was not significantly different between groups, but the overall 5-year survival rate including causes other than gastric cancer was significantly different (p<0.01) at 82% in the elderly group and 67% in the young group.
In the medical care of elderly gastric cancer patients, it is necessary to accurately determine the specific clinicopathological characteristics, and subsequently, an effective surgical treatment method.
背景/目的:由于当前社会老龄化,接受手术治疗的老年胃癌患者数量正在迅速增加。因此,为了确定有效的手术治疗方法,应明确此类患者的临床病理特征。
1979年至2005年间,我院对2010例胃癌患者进行了根治性手术。将老年组(≥80岁)的109例患者与青年组(<80岁)的1901例患者的临床病理特征进行了比较。
在老年组中,胃下三分之一癌、分化型癌以及侵入性较小的手术较为常见。两组之间胃癌特异性5年生存率无显著差异,但包括胃癌以外原因的总体5年生存率有显著差异(p<0.01),老年组为82%,青年组为67%。
在老年胃癌患者的医疗护理中,有必要准确确定具体的临床病理特征,随后确定有效的手术治疗方法。