[菝葜根茎化学成分的研究]

[Studies on chemical constituents of rhizomes of Smilax china].

作者信息

Xu Yan, Liang Jing-Yu, Zou Zhong-Mei

机构信息

Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2008 Nov;33(21):2497-9.

PMID:19149257

Abstract

OBJECTIVE

To study the chemical constituents of the rhizomes of Smilax china.

METHOD

The constituents of the rhizomes of S. china were isolated and purified by repeated silica gel and Sephadex LH-20 chromatography, and their structures were elucidated on the basis of spectral analysis.

RESULT

Thirteen compounds were obtained and identified as kaemperol-7-O-beta-D-glucopyranoside (1), engeletin (2), isoengeletin (3), kaempferol (4), dihydrokaempferol (5), dihydrokaempferol-5-O-P-D-glucopyranoside (6), rutin (7), kaempferol- 5-O-beta-D-glucopyranoside (8), 3, 5, 4'-trihydroxystibene (9), vanillic acid (10), 3, 5-dimethoxy4-O-beta-D-glu-copyranosylcinnamic acid (11), beta-sitosterol (12), and beta-daucosterol (13) , respectively.

CONCLUSION

Compounds 1, 3, 7, 8, and 11 were isolated from this plant for the first time, and compounds 8 and 11 were isolated from the genus Smilax for the first time.

摘要

目的

研究菝葜根茎的化学成分。

方法

采用反复硅胶柱色谱和葡聚糖凝胶LH - 20柱色谱对菝葜根茎的化学成分进行分离纯化，并通过波谱分析鉴定其结构。

结果

分离得到13个化合物，分别鉴定为山柰酚-7-O-β-D-葡萄糖苷（1）、恩格勒苷（2）、异恩格勒苷（3）、山柰酚（4）、二氢山柰酚（5）、二氢山柰酚-5-O-β-D-葡萄糖苷（6）、芦丁（7）、山柰酚-5-O-β-D-葡萄糖苷（8）、3,5,4'-三羟基茋（9）、香草酸（10）、3,5-二甲氧基-4-O-β-D-葡萄糖基肉桂酸（11）、β-谷甾醇（12）和β-胡萝卜苷（13）。