Kohlmeier L, Mensink G, Kohlmeier M
Institute for Social Medicine and Epidemiology, Federal Health Office, Federal Republic of Germany.
Eur Heart J. 1991 Aug;12(8):869-74. doi: 10.1093/eurheartj/12.8.869.
The relationship between coffee consumption and serum lipid levels was studied in a randomly selected sample of 395 young and 385 elderly adults in the Federal Republic of Germany. Analyses were done separately for men and women and for young and older people. After adjustment for body mass index, activity level, smoking, total energy intake, dietary fat, fish, milk, tea and alcohol consumption and oral contraceptive use a statistically significant increase in total serum- and LDL-cholesterol levels with increased coffee consumption was observed in the group of young men only. In this subgroup a difference of 0.11 mmol.l-1 serum cholesterol and of 0.10 mmol.l-1 LDL cholesterol for each additional cup of coffee consumed daily was calculated. This is one of the few studies that includes elderly people. No significant trend was seen between coffee consumption and serum- or LDL-cholesterol levels in the elderly.
在德意志联邦共和国,对随机抽取的395名年轻人和385名老年人进行了咖啡摄入量与血脂水平关系的研究。分别对男性和女性、年轻人和老年人进行了分析。在对体重指数、活动水平、吸烟情况、总能量摄入、膳食脂肪、鱼类、牛奶、茶和酒精摄入量以及口服避孕药使用情况进行调整后,仅在年轻男性组中观察到随着咖啡摄入量增加,血清总胆固醇和低密度脂蛋白胆固醇水平有统计学意义的升高。在这个亚组中,计算出每天多喝一杯咖啡,血清胆固醇增加0.11 mmol·l-1,低密度脂蛋白胆固醇增加0.10 mmol·l-1。这是为数不多的纳入老年人的研究之一。在老年人中,未观察到咖啡摄入量与血清胆固醇或低密度脂蛋白胆固醇水平之间有显著趋势。