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咖啡消费、饮食与脂质。

Coffee consumption, diet, and lipids.

作者信息

Haffner S M, Knapp J A, Stern M P, Hazuda H P, Rosenthal M, Franco L J

出版信息

Am J Epidemiol. 1985 Jul;122(1):1-12. doi: 10.1093/oxfordjournals.aje.a114067.

Abstract

Recent reports suggest that coffee consumption is associated with increased serum cholesterol and triglyceride concentrations. The authors examined the association between serum lipids and coffee consumption and other caffeinated beverages as part of a population-based study of 1,228 women and 923 men, aged 25-64 years, in San Antonio, Texas, studied between October 1979 and November 1982. The study confirmed a positive relationship between coffee consumption and both total and low density lipoprotein cholesterol in both sexes which persisted after adjustment for age, ethnicity, obesity, cigarette smoking, and alcohol consumption. Neither tea nor cola consumption was associated with changes in serum lipids, suggesting that caffeine alone does not exert a direct effect on lipid levels. The possibility was examined that the coffee-cholesterol relationship might be due to a more atherogenic diet consumed by heavy coffee drinkers. In men, per cent calories from both total and saturated fat and dietary cholesterol intake increased with increased coffee consumption. Similar trends were not observed in women, however. The positive relationship between coffee and cholesterol may therefore be due to confounding effects of other aspects of the diet.

摘要

最近的报告表明,饮用咖啡与血清胆固醇和甘油三酯浓度升高有关。作为对得克萨斯州圣安东尼奥市1228名女性和923名年龄在25至64岁之间的男性进行的一项基于人群的研究的一部分,作者研究了血脂与咖啡及其他含咖啡因饮料的消费之间的关联。该研究在1979年10月至1982年11月期间进行。研究证实,在调整年龄、种族、肥胖、吸烟和饮酒因素后,饮用咖啡与男女的总胆固醇和低密度脂蛋白胆固醇均呈正相关。饮用茶和可乐均与血脂变化无关,这表明仅咖啡因对血脂水平没有直接影响。研究探讨了咖啡与胆固醇之间的关系可能是由于大量饮用咖啡者摄入了更易致动脉粥样硬化饮食的可能性。在男性中,随着咖啡饮用量的增加,来自总脂肪和饱和脂肪的卡路里百分比以及膳食胆固醇摄入量均增加。然而,在女性中未观察到类似趋势。因此,咖啡与胆固醇之间的正相关关系可能是由于饮食其他方面的混杂效应。

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