D'Amicis A, Scaccini C, Tomassi G, Anaclerio M, Stornelli R, Bernini A
National Institute of Nutrition, via Ardeatina 546, 00178 Rome, Italy.
Int J Epidemiol. 1996 Jun;25(3):513-20. doi: 10.1093/ije/25.3.513.
Increases in blood lipids have been observed in humans when coffee is brewed by the boiling method. The purpose of this study was to evaluate if giving up Italian coffee might reduce blood cholesterol levels.
Eighty-four normolipidaemic young adult males, after a 3-week baseline (BL), were randomly assigned to three different regimens of coffee consumption: espresso (E), mocha (M), and no coffee, but tea (T). The average coffee consumption during intervention (I) was 3.1 +/- 1.2 and 2.8 +/- 1.1 cups per day for espresso and mocha group respectively (espresso: 25-35 ml/cup; mocha: 40-50 ml/cup). Total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides were measured eight times during the study. Dietary pattern, alcohol consumption, smoking habits, drug use, and anthropometric data were also recorded.
The changes observed in serum cholesterol concentration between baseline and intervention were not statistically different in all groups. The changes were 0.0 mmol/l (T), +0.01 mmol/l (E) and +0.05 mmol/l (M) for total serum cholesterol; 0 mmol/l (T), -0.02 mmol/l (E) and -0. 03 mmol/l (M) for HDL-C; -0.13 mmol/l (T), +0.02 mmol/l (E) and -0. 05 mmol/l (M) for LDL-C. Serum triglycerides showed a significant increase during intervention (P < 0.01 by ANOVA) in all groups with a change of 0.18 mmol/l, 0.18 mmol/l and 0.22 mmol/l, for tea, espresso and mocha group respectively.
The results indicate that coffee brewed in the Italian way does not alter blood levels of total cholesterol, HDL-cholesterol and LDL-cholesterol, since no significant differences were observed in these blood parameters after a 6-week break from coffee consumption.
人们发现,用煮沸法煮咖啡时,人体血脂会升高。本研究旨在评估放弃意大利咖啡是否会降低血液胆固醇水平。
84名血脂正常的年轻成年男性,经过3周的基线期后,被随机分配到三种不同的咖啡饮用方案中:意式浓缩咖啡(E)组、摩卡咖啡(M)组和不喝咖啡但喝茶(T)组。干预期间,意式浓缩咖啡组和摩卡咖啡组的平均咖啡饮用量分别为每天3.1±1.2杯和2.8±1.1杯(意式浓缩咖啡:25 - 35毫升/杯;摩卡咖啡:40 - 50毫升/杯)。在研究期间测量了8次总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和甘油三酯。还记录了饮食模式、饮酒量、吸烟习惯、药物使用情况和人体测量数据。
所有组在基线期和干预期之间观察到的血清胆固醇浓度变化无统计学差异。总血清胆固醇的变化分别为0.0毫摩尔/升(T组)、+0.01毫摩尔/升(E组)和+0.05毫摩尔/升(M组);高密度脂蛋白胆固醇的变化分别为0毫摩尔/升(T组)、-0.02毫摩尔/升(E组)和-0.03毫摩尔/升(M组);低密度脂蛋白胆固醇的变化分别为-0.13毫摩尔/升(T组)、+0.02毫摩尔/升(E组)和-0.05毫摩尔/升(M组)。所有组的血清甘油三酯在干预期间均显著升高(方差分析,P < 0.01),茶组、意式浓缩咖啡组和摩卡咖啡组的变化分别为0.18毫摩尔/升、0.18毫摩尔/升和0.22毫摩尔/升。
结果表明,意大利式冲泡的咖啡不会改变总胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇的血液水平,因为在停止饮用咖啡6周后,这些血液参数未观察到显著差异。