Nishi Yutaro, Mireskandari Kamiar, Khaw Peng, Findl Oliver
Ocular Repair and Regeneration Biology Research Unit, UCL Institute of Ophthalmology, London, United Kingdom.
J Cataract Refract Surg. 2009 Feb;35(2):374-82. doi: 10.1016/j.jcrs.2008.10.054.
The ultimate goal of cataract surgery, besides the restoration of distance visual acuity, is the restoration of accommodation. Lens refilling with an injectable polymer has the potential of restoring accommodation following cataract surgery. Two main difficulties have hampered the success of lens refilling strategies in the past. First was leakage of the injectable material from the capsular bag and second was after-cataract formation resulting in loss of elasticity and opacification of the lens-bag complex. Recently, simplified and highly reproducible lens refilling procedures have been introduced with a potential for clinical application to restore accommodation. We present a summary of the existing methods of lens refilling for restoration of accommodation and some obstacles to clinical application that remain.
白内障手术的最终目标,除了恢复远视力外,是恢复调节功能。用可注射聚合物填充晶状体有可能在白内障手术后恢复调节功能。过去,两个主要困难阻碍了晶状体填充策略的成功。一是可注射材料从囊袋中渗漏,二是后发性白内障的形成导致晶状体 - 囊袋复合体弹性丧失和混浊。最近,已引入了简化且高度可重复的晶状体填充程序,具有临床应用以恢复调节功能的潜力。我们总结了现有的用于恢复调节功能的晶状体填充方法以及仍然存在的临床应用障碍。