Han Ian C, Jaffe Glenn J
Duke Eye Center, Durham, North Carolina 27701, USA.
Am J Ophthalmol. 2009 May;147(5):847-58, 858.e1. doi: 10.1016/j.ajo.2008.11.019. Epub 2009 Feb 6.
To compare retinal thickness (RT) measurements obtained by spectral-domain optical coherence tomography (SD-OCT) and time-domain OCT (TD-OCT) in eyes with and without posterior segment disease diagnoses.
Retrospective, observational chart review.
Scans of 184 healthy and diseased eyes from 106 patients were included in the study. Pair-wise comparisons of RT measurements from SD-OCT machines from 2 different manufacturers and TD-OCT were performed for all scans and with eyes stratified by disease diagnosis.
Foveal thickness measurements obtained from both SD-OCT machines were greater than those measured by TD-OCT, by 51.0 +/- 23.8 microm and 72.5 +/- 30.4 microm, respectively. The foveal thickness difference between the 2 SD-OCT models was 24.3 +/- 19.1 microm. Foveal thickness differences varied by disease diagnosis.
RT measurements obtained by SD-OCT are consistently greater than those obtained by TD-OCT. RT measurement differences may vary by disease diagnosis or by SD-OCT model. Consideration of these measurement differences is essential when OCT-determined RT measurement data are used in clinical settings.
比较在有和没有后段疾病诊断的眼中，通过光谱域光学相干断层扫描（SD-OCT）和时域光学相干断层扫描（TD-OCT）获得的视网膜厚度（RT）测量值。
回顾性观察图表审查。
该研究纳入了来自106例患者的184只健康和患病眼睛的扫描数据。对来自2个不同制造商的SD-OCT机器和TD-OCT的RT测量值进行了成对比较，所有扫描均进行了比较，并按疾病诊断对眼睛进行了分层。
从两台SD-OCT机器获得的黄斑厚度测量值均大于TD-OCT测量值，分别大51.0±23.8微米和72.5±30.4微米。两种SD-OCT模型之间的黄斑厚度差异为24.3±19.1微米。黄斑厚度差异因疾病诊断而异。
SD-OCT获得的RT测量值始终大于TD-OCT获得的测量值。RT测量差异可能因疾病诊断或SD-OCT模型而异。在临床环境中使用OCT确定的RT测量数据时，考虑这些测量差异至关重要。
