MenopauseRx, Inc., Uniontown, PA, USA.
Ther Clin Risk Manag. 2008 Aug;4(4):827-36. doi: 10.2147/tcrm.s3552.
Osteoporosis poses a significant public health issue, causing significant morbidity and mortality. Calcium and vitamin D utilization in the optimization of bone health is often overlooked by patients and health care providers. In addition, the optimal standard of care for osteoporosis should encompass adequate calcium and vitamin D intake. Dietary intake or supplementation with calcium and vitamin D will be reviewed, including recent recommendations for increased vitamin D intake. Compliance to calcium and vitamin D therapy is paramount for effective prevention of osteoporotic fractures. A recently released algorithm (FRAX) estimating absolute fracture risk allows the health care provider to decide when pharmacologic therapy is warranted in addition to calcium and vitamin D. When pharmacologic therapy is advised, continued use of calcium and vitamin D is recommended for optimal fracture risk reduction. A 'bricks and mortar' analogy is often helpful when counseling patients and this analogy will be explained. This manuscript reviews relevant data related to calcium and vitamin D use for patients at risk for fracture due to bone loss.
骨质疏松症是一个重大的公共卫生问题,可导致严重的发病率和死亡率。患者和医疗保健提供者往往忽略了钙和维生素 D 在优化骨骼健康方面的作用。此外,骨质疏松症的最佳标准护理应包括足够的钙和维生素 D 摄入。将对钙和维生素 D 的饮食摄入或补充进行审查,包括最近增加维生素 D 摄入的建议。钙和维生素 D 治疗的依从性对于预防骨质疏松性骨折至关重要。最近发布的一种(FRAX)评估绝对骨折风险的算法允许医疗保健提供者决定何时需要除钙和维生素 D 以外的药物治疗。当建议药物治疗时,建议继续使用钙和维生素 D 以最大程度地降低骨折风险。在为因骨质流失而有骨折风险的患者提供咨询时,“砖头和灰浆”的类比通常很有帮助,下面将对此进行解释。本文综述了与因骨质流失而有骨折风险的患者使用钙和维生素 D 相关的相关数据。