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基于同源性推断的蛋白质功能注释。

Protein function annotation by homology-based inference.

机构信息

Department of Biological Chemistry, The Hebrew University of Jerusalem, Sudarsky Center, Jerusalem 91904, Israel.

出版信息

Genome Biol. 2009 Feb 2;10(2):207. doi: 10.1186/gb-2009-10-2-207.

Abstract

With many genomes now sequenced, computational annotation methods to characterize genes and proteins from their sequence are increasingly important. The BioSapiens Network has developed tools to address all stages of this process, and here we review progress in the automated prediction of protein function based on protein sequence and structure.

摘要

随着越来越多的基因组被测序,基于序列来描述基因和蛋白质的计算注释方法变得越来越重要。BioSapiens 网络已经开发了工具来解决这个过程的所有阶段,在这里我们回顾了基于蛋白质序列和结构的蛋白质功能自动预测的进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87b5/2688287/f232dc7b3066/gb-2009-10-2-207-1.jpg

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