State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, and Graduate University of the Chinese Academy of Sciences, Changchun 130022, PR China.
Anal Chem. 2009 Mar 15;81(6):2378-82. doi: 10.1021/ac802193c.
We first reported that polyvinylpyrrolidone-protected graphene was dispersed well in water and had good electrochemical reduction toward O(2) and H(2)O(2). With glucose oxidase (GOD) as an enzyme model, we constructed a novel polyvinylpyrrolidone-protected graphene/polyethylenimine-functionalized ionic liquid/GOD electrochemical biosensor, which achieved the direct electron transfer of GOD, maintained its bioactivity and showed potential application for the fabrication of novel glucose biosensors with linear glucose response up to 14 mM.
我们首次报道了聚乙烯吡咯烷酮保护的石墨烯在水中分散良好，对 O(2) 和 H(2)O(2) 具有良好的电化学还原性能。以葡萄糖氧化酶 (GOD) 为模型酶，构建了一种新型的聚乙烯吡咯烷酮保护的石墨烯/聚乙烯亚胺功能化离子液体/GOD 电化学生物传感器，实现了 GOD 的直接电子转移，保持了其生物活性，并有望用于制备新型葡萄糖生物传感器，其线性葡萄糖响应范围可达 14 mM。
