Santos-Silva Rogerio, Tufik Sergio, Conway Silvia G, Taddei Jose Augusto, Bittencourt Lia Rita A
Discipline of Medicine and Biology of Sleep, Department of Psychobiology, Univ Fed Sao Paulo - UNIFESP, Rua Napoleao de Barros 925, 1o andar, CEP 04024-002, Sao Paulo/SP, Brazil.
Sleep Med. 2009 Jun;10(6):679-85. doi: 10.1016/j.sleep.2008.11.001. Epub 2009 Feb 18.
To present the rational design, sampling, and procedures utilized in an Epidemiologic Sleep Study carried out in 2007 to establish the epidemiologic profile of sleep disorders in the adult population of a large metropolitan city, Sao Paulo, Brazil.
A population-based survey adopting a probabilistic three-stage cluster sample of Sao Paulo was used to represent the population according to gender, age (20-80 years), and socioeconomic class. Questionnaires, actigraphy, polysomnography (PSG), and blood samples were collected to investigate associations between sleep patterns and disturbances according to social-demographic status, activity/rest cycle, physical activity habits, mood disturbances, memory complaints, sexual dysfunction in males, drug addiction, genetic markers, and anthropometric, clinical, biochemical, hematological, endocrine, immunologic, and inflammatory indicators.
A total of 1101 questionnaires were administered at home. A total of 156 volunteers were substituted, who were equivalent to the remaining sample in terms of age, gender, and socioeconomic class. A total of 1042 volunteers underwent PSG recordings at a Sleep Institute, and the refusal rate was 5.4%.
The Sao Paulo Sleep Study is a pioneering investigation, incorporating and integrating up-to-date methodologies for understanding sleep profiles and sleep disorders in large populations. This study will provide reliable information for the planning of health policies and programs aimed to control such disorders and their consequences in the city of Sao Paulo and similar urban environments.
介绍2007年进行的一项流行病学睡眠研究中所采用的合理设计、抽样方法及程序，该研究旨在确定巴西大城市圣保罗成年人群睡眠障碍的流行病学特征。
采用基于人群的调查，对圣保罗进行概率性三阶段整群抽样，以按性别、年龄（20 - 80岁）和社会经济阶层来代表人群。收集问卷、活动记录仪数据、多导睡眠图（PSG）及血样，以根据社会人口统计学状况、活动/休息周期、体育活动习惯、情绪障碍、记忆问题、男性性功能障碍、药物成瘾、基因标记以及人体测量、临床、生化、血液学、内分泌、免疫和炎症指标来研究睡眠模式与障碍之间的关联。
共在家中发放了1101份问卷。共有156名志愿者被替换，这些志愿者在年龄、性别和社会经济阶层方面与其余样本相当。共有1042名志愿者在睡眠研究所接受了PSG记录，拒绝率为5.4%。
圣保罗睡眠研究是一项开创性调查，纳入并整合了最新方法以了解大群体中的睡眠特征和睡眠障碍。本研究将为旨在控制圣保罗市及类似城市环境中此类障碍及其后果的卫生政策和项目规划提供可靠信息。
