He Su-Li, Yan Ren-Yi, Zuo Li, Chen Ruo-Yun
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, PR China.
Planta Med. 2009 May;75(6):641-6. doi: 10.1055/s-0029-1185378. Epub 2009 Feb 23.
Twelve ENT-abietane and ENT-kaurane type diterpenoids, 1- 12, including five new compounds 1- 5, were isolated from the roots of Suregada glomerulata. The structures of the new compounds were elucidated on the basis of 1D and 2D NMR and other spectroscopic studies, and the structures of 1 and 2 were confirmed by X-ray crystallography. Cytotoxic activities against five human tumor cell lines were evaluated.
从团花叶下珠的根部分离出12种对映-松香烷型和对映-贝壳杉烷型二萜类化合物，1-12，其中包括5个新化合物1-5。通过一维和二维核磁共振及其他光谱研究阐明了新化合物的结构，1和2的结构通过X射线晶体学得到证实。评估了对5种人类肿瘤细胞系的细胞毒活性。
