[利用人胎儿腺垂体几个细胞群早期分化现象的半薄切片进行免疫细胞化学研究]

[Immunocytochemical study using semi-thin sections of the phenomena of early differentiation in several cell populations of the human fetal adenohypophysis].

作者信息

Bugnon C, Lenys D, Bloch B, Fellmann D

出版信息

C R Seances Soc Biol Fil. 1976;170(5):975-82.

Abstract

Immunocytological investigations have been performed on semi-thin sections of human fetal pituitaries ranging in fetal age from 6 to 26 weeks. Corticotrophs can be revealed by anti-ACTH (1-24), anti-ACTH (17-39) and anti-beta MSH but not by anti-alpha MSH immunesera from the 8th week. Somatotrophs are revealed with anti-human STH from 9th week. Differentiating cells containing only alpha subunits of glycoproteic hormones are present from 8th to 12th week. At 13th week beta subunits of TSH can be revealed immunocytologically in thyreotrophs. Beta subunits of LH or FSH can be detected in same gonadotrophic cells only from 15th week.

摘要

对胎龄为6至26周的人类胎儿垂体半薄切片进行了免疫细胞学研究。从第8周起，促肾上腺皮质激素细胞可用抗促肾上腺皮质激素（1 - 24）、抗促肾上腺皮质激素（17 - 39）和抗β促黑素血清显示，但不能用抗α促黑素免疫血清显示。从第9周起，生长激素细胞可用抗人生长激素显示。仅含糖蛋白激素α亚基的分化细胞在第8至12周出现。在第13周，促甲状腺激素细胞中可通过免疫细胞学方法显示促甲状腺激素的β亚基。促黄体生成素或促卵泡生成素的β亚基仅从第15周起可在相同的促性腺激素细胞中检测到。

相似文献

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[Immunocytochemical study using semi-thin sections of the phenomena of early differentiation in several cell populations of the human fetal adenohypophysis].[利用人胎儿腺垂体几个细胞群早期分化现象的半薄切片进行免疫细胞化学研究]

C R Seances Soc Biol Fil. 1976;170(5):975-82.

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Functional prenatal development of anencephalic and normal anterior pituitary glands. In human and experimental animals studied by peroxidase-labeled antibody method.无脑儿和正常垂体前叶的功能性产前发育。在通过过氧化物酶标记抗体法研究的人类和实验动物中。

Acta Pathol Jpn. 1977 Jul;27(4):495-509.

引用本文的文献

1

Immunohistochemical localization of FSH and LH in the pars distalis of vervet (Cercopithecus aethiops) and baboon (Papio hamadryas) pituitaries.促卵泡激素（FSH）和促黄体生成素（LH）在绿猴（非洲长尾猴）和狒狒垂体远侧部的免疫组织化学定位。

Cell Tissue Res. 1981;217(2):245-57. doi: 10.1007/BF00233578.

2

Immunocytochemical study of the ontogenesis of the hypothalamic somatostatin-containing neurons in the human fetus.人胎儿下丘脑含生长抑素神经元发生的免疫细胞化学研究。

Cell Tissue Res. 1977 Sep 30;183(3):319-28. doi: 10.1007/BF00220639.

3

Infundibular neurons of the human hypothalamus simultaneously reactive with antisera against endorphins, ACTH, MSH and beta-LPH.人类下丘脑的漏斗神经元可同时与抗内啡肽、促肾上腺皮质激素、促黑素细胞激素及β-促脂解素的抗血清发生反应。

Cell Tissue Res. 1979 Jun 27;199(2):177-96. doi: 10.1007/BF00236130.

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