Sugimoto Sachiko, Nakamura Seikou, Yamamoto Sachiyo, Yamashita Chihiro, Oda Yoshimi, Matsuda Hisashi, Yoshikawa Masayuki
Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8412, Japan.
Chem Pharm Bull (Tokyo). 2009 Mar;57(3):257-61. doi: 10.1248/cpb.57.257.
The methanolic extract from the leaves of Ilex paraguariensis (Aquifoliaceae) was found to show an inhibitory activity on porcine pancreatic lipase. From the methanolic extract, three new triterpene oligoglycosides, mateglycosides A, B, and C, were isolated together with 18 known compounds. The chemical structures of new oligoglycosides were elucidated on the basis of chemical and physicochemical evidence. Several constituents showed inhibitory activities on pancreatic lipase.
巴拉圭冬青（冬青科）叶的甲醇提取物对猪胰脂肪酶具有抑制活性。从该甲醇提取物中分离出三种新的三萜寡糖苷，即马黛糖苷A、B和C，以及18种已知化合物。基于化学和物理化学证据阐明了新寡糖苷的化学结构。几种成分对胰脂肪酶具有抑制活性。
