Goldberg Brian D, Motaghian Nezam S M R, Jillella Priyanka, Bouma Brett E, Tearney Guillermo J
Harvard Medical School and the Wellman Center for Photomedicine, Massachusetts General Hospital, 50 BlossomSt., Boston, MA 02114, USA.
Opt Express. 2009 Mar 2;17(5):3619-29. doi: 10.1364/oe.17.003619.
Point of care (POC) medical technologies require portable, small, robust instrumentation for practical implementation. In their current embodiment, optical frequency domain imaging (OFDI) systems employ large form-factor wavelength-swept lasers, making them impractical in the POC environment. Here, we describe a first step toward a POC OFDI system by demonstrating a miniaturized swept-wavelength source. The laser is based on a tunable optical filter using a reflection grating and a miniature resonant scanning mirror. The laser achieves 75 nm of bandwidth centered at 1340 nm, a 0.24 nm instantaneous line width, a 15.3 kHz repetition rate with 12 mW peak output power, and a 30.4 kHz A-line rate when utilizing forward and backward sweeps. The entire laser system is approximately the size of a deck of cards and can operate on battery power for at least one hour.
即时医疗(POC)技术需要便携、小巧且坚固的仪器才能实际应用。在当前的形式中,光学频域成像(OFDI)系统采用的是大尺寸的波长扫描激光器,这使得它们在即时医疗环境中不实用。在此,我们通过展示一种小型化的扫描波长源,描述了迈向即时医疗OFDI系统的第一步。该激光器基于一个使用反射光栅的可调谐光学滤波器和一个微型谐振扫描镜。该激光器在1340nm中心波长处实现了75nm的带宽、0.24nm的瞬时线宽、15.3kHz的重复频率以及12mW的峰值输出功率,在使用正向和反向扫描时A线速率为30.4kHz。整个激光系统大约只有一副扑克牌大小,并且可以使用电池供电至少一小时。