Wang Yimin, Fawzi Amani, Tan Ou, Gil-Flamer John, Huang David
Center for Ophthalmic Optics & Lasers, Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Opt Express. 2009 Mar 2;17(5):4061-73. doi: 10.1364/oe.17.004061.
We present human retinal blood flow investigation for diabetic patients using Doppler Fourier domain optical coherence tomography (FDOCT). The scanning pattern consisted of two concentric circles around the optic nerve head. The blood flow in one patient with diabetes and no retinpathy and another patient with treated proliferative diabetic retinopathy were measured. The patient without retinopathy showed a total blood flow value at the lower level of the normal range. The flow distribution between superior and inferior retina was balanced. The patient with diabetic retinopathy had a flow value lower than the normal people. Our study shows that Doppler FD-OCT can be used to evaluate the total retinal blood flow in patients with retinal diseases.
我们展示了使用多普勒傅里叶域光学相干断层扫描（FDOCT）对糖尿病患者进行的人视网膜血流研究。扫描模式由围绕视神经乳头的两个同心圆组成。测量了一名患有糖尿病但无视网膜病变的患者和另一名接受治疗的增殖性糖尿病视网膜病变患者的血流情况。没有视网膜病变的患者显示总血流值处于正常范围的较低水平。视网膜上下层之间的血流分布是平衡的。患有糖尿病视网膜病变的患者血流值低于正常人。我们的研究表明，多普勒频域光学相干断层扫描可用于评估视网膜疾病患者的视网膜总血流。
