居住在10个国家的欧洲中老年社区居民的衰弱患病率。

Prevalence of frailty in middle-aged and older community-dwelling Europeans living in 10 countries.

作者信息

Santos-Eggimann Brigitte, Cuénoud Patrick, Spagnoli Jacques, Junod Julien

机构信息

Department of Community Medicine and Health, Institute of Social and Preventive Medicine, University Hospital Center and University of Lausanne, Switzerland.

出版信息

J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):675-81. doi: 10.1093/gerona/glp012. Epub 2009 Mar 10.

Abstract

BACKGROUND

Frailty is an indicator of health status in old age. Its frequency has been described mainly for North America; comparable data from other countries are lacking. Here we report on the prevalence of frailty in 10 European countries included in a population-based survey.

METHODS

Cross-sectional analysis of 18,227 randomly selected community-dwelling individuals 50 years of age and older, enrolled in the Survey of Health, Aging and Retirement in Europe (SHARE) in 2004. Complete data for assessing a frailty phenotype (exhaustion, shrinking, weakness, slowness, and low physical activity) were available for 16,584 participants. Prevalences of frailty and prefrailty were estimated for individuals 50-64 years and 65 years of age and older from each country. The latter group was analyzed further after excluding disabled individuals. We estimated country effects in this subset using multivariate logistic regression models, controlling first for age, gender, and then demographics and education.

RESULTS

The proportion of frailty (three to five criteria) or prefrailty (one to two criteria) was higher in southern than in northern Europe. International differences in the prevalences of frailty and prefrailty for 65 years and older group persisted after excluding the disabled. Demographic characteristics did not account for international differences; however, education was associated with frailty. Controlling for education, age and gender diminished the effects of residing in Italy and Spain.

CONCLUSIONS

A higher prevalence of frailty in southern countries is consistent with previous findings of a north-south gradient for other health indicators in SHARE. Our data suggest that socioeconomic factors like education contribute to these differences in frailty and prefrailty.

摘要

背景

衰弱是老年健康状况的一个指标。其发生率主要在北美地区有描述;其他国家缺乏可比数据。在此,我们报告一项基于人群的调查中10个欧洲国家的衰弱患病率。

方法

对2004年参加欧洲健康、老龄化与退休调查(SHARE)的18227名随机选取的50岁及以上社区居住个体进行横断面分析。16584名参与者可获得用于评估衰弱表型(疲惫、消瘦、虚弱、行动迟缓及低体力活动)的完整数据。估计了每个国家50 - 64岁以及65岁及以上个体的衰弱和衰弱前期患病率。在排除残疾个体后,对后一组进行了进一步分析。我们使用多变量逻辑回归模型估计该亚组中的国家效应,首先控制年龄、性别,然后控制人口统计学和教育因素。

结果

衰弱(三到五个标准)或衰弱前期(一到两个标准)的比例在南欧高于北欧。在排除残疾个体后,65岁及以上组的衰弱和衰弱前期患病率的国际差异仍然存在。人口统计学特征不能解释国际差异;然而,教育与衰弱有关。控制教育、年龄和性别后,居住在意大利和西班牙的影响减弱。

结论

南部国家较高的衰弱患病率与SHARE中其他健康指标的南北梯度先前研究结果一致。我们的数据表明,像教育这样的社会经济因素导致了衰弱和衰弱前期的这些差异。

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