Division of Geriatric Medicine, Hospital Virgen del Valle, Complejo Hospitalario de Toledo, Toledo, Spain.
J Nutr Health Aging. 2011 Dec;15(10):852-6. doi: 10.1007/s12603-011-0075-8.
To assess the prevalence of the frailty syndrome and its associated variables among the older adult population in the province of Toledo (Spain).
Data were taken from the Toledo Study for Healthy Aging, a population-based study conducted on 2,488 individuals aged 65 years and older. Study participants were selected by a two-stage random sampling from the municipal census of Toledo, covering both institutionalized and community dwelling persons from rural and urban settings. Data were collected from 2006 to 2009, and included information on social support, activities of daily living, comorbidity, physical activity, quality of life, depressive symptoms, and cognitive function. In addition, a nurse collected anthropometric data, conducted tests of physical performance (walk speed, upper and lower extremities strength, and the stand-and-sit from a chair test) and obtained a blood sample. The diagnosis of the frailty syndrome was based on the Fried criteria (weakness, low speed, low physical activity, exhaustion, and weight loss).
In total, 41.8% (95% confidence interval [CI] 39.4-44.2%) of the study participants were prefrail, and 8.4% (95% CI 7.1-9.8%) were frail. There were no differences in the prevalence of frailty by sex, level of education, occupation, marital status, or place of residence. The frequency of the frailty syndrome increased with age, and was higher in those with disability, depression, hip fracture and other comorbidity, such as cardiovascular disease and disorders of the central nervous system.
The prevalence of the frailty syndrome in older Spanish adults is high and similar to that reported in other populations in the Mediterranean basin.
评估托莱多省(西班牙)老年人群中衰弱综合征的流行情况及其相关变量。
数据来自托莱多健康老龄化研究,这是一项基于人群的研究,共纳入 2488 名 65 岁及以上的老年人。研究对象通过托莱多市人口普查的两阶段随机抽样选择,包括农村和城市地区的机构和社区居住者。数据收集于 2006 年至 2009 年,包括社会支持、日常生活活动、共病、身体活动、生活质量、抑郁症状和认知功能等信息。此外,护士还收集了人体测量数据、进行了身体表现测试(步行速度、上下肢力量以及从椅子上站立和坐下测试),并采集了血液样本。衰弱综合征的诊断基于 Fried 标准(虚弱、速度慢、身体活动少、疲惫和体重减轻)。
研究参与者中,41.8%(95%置信区间[CI]39.4-44.2%)为衰弱前期,8.4%(95% CI 7.1-9.8%)为衰弱。性别、教育程度、职业、婚姻状况或居住地对衰弱的流行率没有影响。衰弱综合征的发生率随年龄增长而增加,在残疾、抑郁、髋部骨折和其他共病(如心血管疾病和中枢神经系统疾病)患者中更高。
西班牙老年人群中衰弱综合征的流行率较高,与地中海盆地其他人群报告的相似。