Vahratian Anjel, Barber Jennifer S, Lawrence Jean M, Kim Catherine
Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA. Anjel Vahratian,
Diabetes Care. 2009 Jun;32(6):1026-31. doi: 10.2337/dc08-2105. Epub 2009 Mar 11.
To examine contraceptive practices among diabetic women and obese women.
We analyzed the responses of 5,955 participants aged 20-44 years in the 2002 National Survey for Family Growth. Diabetes, BMI, desire for pregnancy, history of infertility treatment, sexual activity, parity, and demographic variables (age, race/ethnicity, education, marital status, income, insurance, and smoking history) were obtained by self-report. Lack of contraception was defined as absence of hormonal-, barrier-, or sterilization-based methods. Associations among contraception, diabetes, and BMI category were assessed in multivariable logistic regression models in nonsterile, sexually active women.
In unadjusted comparisons among sexually active women who were not sterilized, women with diabetes were more likely to lack contraception than women without diabetes (odds ratio [OR] 2.61 [95% CI 1.22-5.58]). Women with BMI >or=35 kg/m(2) were more likely to lack contraception than women with BMI <25 kg/m(2)(1.63 [1.16-2.28]), but associations between contraception use and lesser degrees of overweight and obesity were not significant. In multivariable models, women who were older (aged >or=30 vs. 20-29 years), were of non-Hispanic black race, were cohabitating, had a history of infertility treatment, and desired or were ambivalent about pregnancy were significantly more likely to lack contraception. The associations among diabetes, BMI, and contraception were no longer significant after these adjustments.
Older women with diabetes and obesity who desire pregnancy, regardless of pregnancy intention, should be targeted for preconceptive management.
研究糖尿病女性和肥胖女性的避孕措施。
我们分析了2002年全国家庭生育调查中5955名年龄在20 - 44岁之间参与者的回答。通过自我报告获取糖尿病、体重指数(BMI)、怀孕意愿、不孕治疗史、性活动、生育情况以及人口统计学变量(年龄、种族/族裔、教育程度、婚姻状况、收入、保险和吸烟史)。未采取避孕措施被定义为未使用激素、屏障或绝育类避孕方法。在未绝育、有性活动的女性中,通过多变量逻辑回归模型评估避孕措施、糖尿病和BMI类别之间的关联。
在未绝育的有性活动女性的未经调整比较中,糖尿病女性比非糖尿病女性更有可能未采取避孕措施(优势比[OR]为2.61[95%置信区间1.22 - 5.58])。BMI≥35 kg/m²的女性比BMI<25 kg/m²的女性更有可能未采取避孕措施(1.63[1.16 - 2.28]),但避孕措施使用与较轻程度超重和肥胖之间的关联不显著。在多变量模型中,年龄较大(≥30岁与20 - 29岁相比)、非西班牙裔黑人种族、同居、有不孕治疗史且想要怀孕或对怀孕态度矛盾的女性显著更有可能未采取避孕措施。经过这些调整后,糖尿病、BMI和避孕之间的关联不再显著。
无论怀孕意愿如何,有怀孕意愿的糖尿病和肥胖老年女性都应作为孕前管理的目标人群。