铑催化的二炔与烯酮的分子内[2+2+2]环化反应。
Intramolecular rhodium-catalyzed [2+2+2] cyclizations of diynes with enones.
作者信息
Jones Amanda L, Snyder John K
机构信息
Center for Chemical Methodology and Library Development, and the Department of Chemistry, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA.
出版信息
J Org Chem. 2009 Apr 3;74(7):2907-10. doi: 10.1021/jo9001678.
Abstract
The Rh(I)-catalyzed inter- and intramolecular [2+2+2] cyclization of diynes with alpha,beta-unsaturated enones proceeds with microwave promotion in good yields. This chemistry was applied to the synthesis of (-)-alcyopterosin I.
摘要
铑（I）催化的二炔与α，β-不饱和烯酮的分子间和分子内[2+2+2]环化反应在微波促进下以良好的产率进行。该化学方法被应用于（-）-alcyopterosin I的合成。
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