Ghodsi S Zahra, Orawa Helmut, Zouboulis Christos C
Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran.
J Invest Dermatol. 2009 Sep;129(9):2136-41. doi: 10.1038/jid.2009.47. Epub 2009 Mar 12.
A cross-sectional, community-based study was performed to determine the prevalence and severity of acne vulgaris in adolescents and of factors influencing the acne severity risk. The presence of acne was clinically determined and the secondary outcome measures of family acne history and the relation of acne to nutrition habits, emotional stress, menstruation, and smoking were recorded in a questionnaire. A representative sample of 1,002 pupils aged 16+/-0.9 years was enrolled. The overall acne prevalence was 93.3, 94.4% for boys and 92.0% for girls. Moderate to severe acne was observed in 14%. The prevalence of moderate to severe acne was 19.9% in pupils with and 9.8% in those without a family history of acne (P<0.0005; OR: 2.3). Acne severity risk increased with the number of family members with acne history. A mother with acne history influenced the severity of acne the most. Increasing pubertal age, seborrhea, the premenstrual phase, mental stress, and sweet and oily foods were recognized as risk factors for moderate to severe acne. In contrast, gender, spicy foods, and smoking were not associated with acne severity. In conclusion, acne is a common disorder in Iranian adolescents, with a low rate of moderate to severe acne. A genetic background is suggested, with mother's acne history being the most important prognostic factor. Skin quality and certain nutrition habits may affect acne severity.
开展了一项基于社区的横断面研究,以确定青少年寻常痤疮的患病率和严重程度,以及影响痤疮严重程度风险的因素。通过临床诊断痤疮的存在情况,并通过问卷调查记录家族痤疮病史的次要结果指标,以及痤疮与营养习惯、情绪压力、月经和吸烟的关系。纳入了1002名年龄在16±0.9岁的学生作为代表性样本。总体痤疮患病率为93.3%,男孩为94.4%,女孩为92.0%。观察到中度至重度痤疮的比例为14%。有家族痤疮病史的学生中,中度至重度痤疮的患病率为19.9%,无家族痤疮病史的学生中为9.8%(P<0.0005;比值比:2.3)。痤疮严重程度风险随着有痤疮病史的家庭成员数量增加而升高。有痤疮病史的母亲对痤疮严重程度的影响最大。青春期年龄增加、皮脂溢、经前期、精神压力以及甜食和油腻食物被认为是中度至重度痤疮的风险因素。相比之下,性别、辛辣食物和吸烟与痤疮严重程度无关。总之,痤疮在伊朗青少年中是一种常见疾病,中度至重度痤疮的发生率较低。提示存在遗传背景,母亲的痤疮病史是最重要的预后因素。皮肤质量和某些营养习惯可能会影响痤疮严重程度。