Nylen Kirk, Likhodii Sergei, Burnham W McIntyre
Department of Pharmacology and University of Toronto Epilepsy Research Program (UTERP), University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Neurotherapeutics. 2009 Apr;6(2):402-5. doi: 10.1016/j.nurt.2009.01.021.
The ketogenic diet is a high-fat, low-carbohydrate diet used to treat drug-resistant seizures, especially in children. A number of possible mechanisms of action have been proposed to explain the anticonvulsant effects of the diet. Four of these hypothetical mechanisms are discussed in the present article: the pH hypothesis, the metabolic hypotheses, the amino acid hypothesis, and the ketone hypothesis.
生酮饮食是一种高脂肪、低碳水化合物的饮食，用于治疗耐药性癫痫发作，尤其是在儿童中。人们提出了许多可能的作用机制来解释这种饮食的抗惊厥作用。本文讨论了其中四种假设机制：pH值假说、代谢假说、氨基酸假说和酮假说。
