西咪替丁与胃黏膜屏障
Cimetidine and the gastric mucosal barrier.
作者信息
Kenyon G S, Ansell I F, Carter D C
出版信息
Gut. 1977 Aug;18(8):631-5. doi: 10.1136/gut.18.8.631.
Abstract
The histamine H2-receptor antagonist, cimetidine, when given topically or parenterally, did not affect net luminal Na+ gain or net luminal H+ loss in vagally-denervated pouches of antrectomised dogs. Cimetidine did not affect disruption of the mucosal barrier by 5 mmol/l or 20 mmol/l sodium taurocholate.
摘要
组胺H2受体拮抗剂西咪替丁，经局部或胃肠外给药时，对切除胃窦的犬迷走神经切断后的胃囊管腔内净钠增加或净氢离子减少均无影响。西咪替丁对5毫摩尔/升或20毫摩尔/升牛磺胆酸钠引起的黏膜屏障破坏也无影响。
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引用本文的文献
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本文引用的文献
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GASTRIC MUCOSAL INJURY BY FATTY AND ACETYLSALICYLIC ACIDS.脂肪酸和乙酰水杨酸所致的胃黏膜损伤
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Ethanol damage to canine oxyntic glandular mucosa.乙醇对犬胃泌酸腺黏膜的损伤。
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Etiology of gastric ulcer.胃溃疡的病因。
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Failure of ischemia to break the dog's gastric mucosal barrier.缺血未能破坏犬的胃黏膜屏障。
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Definition and antagonism of histamine H 2 -receptors.组胺H2受体的定义与拮抗作用。
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7
Source of the histamine released during damage to the gastric mucosa by acetic acid.乙酸损伤胃黏膜时释放的组胺来源。
Gastroenterology. 1968 Jan;54(1):8-15.
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Histamine liberation by gastric mucosa of pylorus-ligated rats damaged by acetic or salicylic acids.乙酸或水杨酸损伤的幽门结扎大鼠胃黏膜释放组胺的情况。
Proc Soc Exp Biol Med. 1966 Feb;121(2):384-6. doi: 10.3181/00379727-121-30784.
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Fluid produced by the gastric mucosa during damage by acetic and salicylic acids.胃黏膜在受到乙酸和水杨酸损伤时产生的液体。
Gastroenterology. 1966 Apr;50(4):487-99.
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