Feldchtein F, Gelikonov G, Gelikonov V, Kuranov R, Sergeev A, Gladkova N, Shakhov A, Shakhova N, Snopova L, Terent'eva A, Zagainova E, Chumakov Y, Kuznetzova I
Opt Express. 1998 Sep 14;3(6):257-70. doi: 10.1364/oe.3.000257.
We report results of application of our endoscopic optical coherence tomography (EOCT) system in clinical experiments to image human internal organs. Based on the experience of studying more than 100 patients, we make first general conclusions on the place and capabilities of this method in diagnosing human mucous membranes. It is demonstrated that EOCT can serve for several clinical purposes such as performing directed biopsy, monitoring functional states of human body, guiding surgical and other treatments and monitoring post-operative recovery processes. We show that applications of OCT are more informative in the case of internal organs covered by epithelium separated from underlying stroma by a smooth basal membrane and therefore concentrate on the results of the EOCT study of three internal organs, namely of larynx, bladder, and uterine cervix. Finally, we report first examination of internal organs in abdomen with the use of laparoscopic OCT.
我们报告了我们的内镜光学相干断层扫描（EOCT）系统在临床实验中用于对人体内部器官成像的结果。基于对100多名患者的研究经验，我们首次对该方法在诊断人体黏膜方面的地位和能力得出了一般性结论。结果表明，EOCT可用于多种临床目的，如进行定向活检、监测人体功能状态、指导手术及其他治疗以及监测术后恢复过程。我们发现，对于上皮组织由光滑基底膜与下方基质分隔的内部器官，光学相干断层扫描（OCT）的应用信息更为丰富，因此我们重点关注了EOCT对三个内部器官，即喉部、膀胱和子宫颈的研究结果。最后，我们报告了首次使用腹腔镜OCT对腹部内部器官进行的检查。
