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综述:用于高通量分析应用的微米级和纳米级分子印迹聚合物

Review: micro- and nanosized molecularly imprinted polymers for high-throughput analytical applications.

作者信息

Tokonami Shiho, Shiigi Hiroshi, Nagaoka Tsutomu

机构信息

Frontier Science Innovation Center, Osaka Prefecture University, 1-2 Gakuen-cho, Naka-ku, Sakai 599-8570, Japan.

出版信息

Anal Chim Acta. 2009 May 8;641(1-2):7-13. doi: 10.1016/j.aca.2009.03.035. Epub 2009 Mar 25.

Abstract

This review covers the analytical properties and applications of micro- and nanostructured molecularly imprinted polymers. The first two parts focused on their intrinsic and receptor properties specific to 0-1 dimensional MIP nanoobjects. The third part reviews the recent publication regarding the 2-3D patterned MIP structures mainly focusing on their sensor and microarray applications. Several patterning techniques that can be used for the fabrication of MIP microsensors/arrays are explained. Finally, a recent publication on some other nanomaterials (metal and semiconductor nanoparticles), which are compatible with MIP receptors to enhance the sensitivity, is discussed.

摘要

本综述涵盖了微纳结构分子印迹聚合物的分析特性及应用。前两部分聚焦于其特定于0 - 1维分子印迹聚合物纳米对象的固有特性和受体特性。第三部分回顾了近期关于二维和三维图案化分子印迹聚合物结构的出版物,主要关注其传感器和微阵列应用。解释了几种可用于制造分子印迹聚合物微传感器/阵列的图案化技术。最后,讨论了近期关于一些其他纳米材料(金属和半导体纳米颗粒)的出版物,这些纳米材料与分子印迹聚合物受体兼容以提高灵敏度。

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