三种来自华桑茎皮的新型狄尔斯-阿尔德型加合物。

Three new Diels-Alder type adducts from the stem bark of Morus cathayana.

作者信息

Zhang Qing-Jian, Ni Gang, Wang Ying-Hong, Chen Ruo-Yun, Yu De-Quan

机构信息

The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Peking Union Medical College, Ministry of Education, Beijing, China.

出版信息

J Asian Nat Prod Res. 2009;11(3):267-73. doi: 10.1080/10286020902767690.

DOI:10.1080/10286020902767690

PMID:19408152

Abstract

Three new Diels-Alder type adducts cathayanons C (1), D (2), and E (3), together with one known compound sanggenon C (4), were isolated from the stem bark of Morus cathayana. Their structures were fully elucidated by spectroscopic and chemical methods. Compound 2 showed good anti-oxidation activity with the inhibitory rate of malondialdehyde being 88% at a concentration of 10(- 6) mol/l.

摘要

从桑茎皮中分离得到3个新型狄尔斯-阿尔德型加合物（1-3）和1个已知化合物桑根酮C（4）。通过光谱和化学方法对其结构进行了全面解析。化合物2具有良好的抗氧化活性，在浓度为10（-6）mol/L时对丙二醛的抑制率为88%。