Walline J J, Jones L A, Sinnott L T
The Ohio State University College of Optometry, Columbus, Ohio, USA.
Br J Ophthalmol. 2009 Sep;93(9):1181-5. doi: 10.1136/bjo.2008.151365. Epub 2009 May 4.
BACKGROUND/AIMS: Anecdotal evidence indicates that corneal reshaping contact lenses may slow myopia progression in children. The purpose of this investigation is to determine whether corneal reshaping contact lenses slow eye growth.
Forty subjects were fitted with corneal reshaping contact lenses. All subjects were 8 to 11 years and had between -0.75 D and -4.00 D myopia with less than 1.00 D astigmatism. Subjects were age-matched to a soft contact lens wearer from another myopia control study. A-scan ultrasound was performed at baseline and annually for 2 years.
Twenty-eight of 40 (70%) subjects wore corneal reshaping contact lenses for 2 years. The refractive error and axial length were similar between the two groups at baseline. The corneal reshaping group had an annual rate of change in axial lengths that was significantly less than the soft contact lens wearers (mean difference in annual change = 0.16 mm, p = 0.0004). Vitreous chamber depth experienced similar changes (mean difference in annual change = 0.10 mm, p = 0.006).
Results confirm previous reports of slowed eye growth following corneal reshaping contact lens wear.
背景/目的：轶事证据表明，角膜塑形隐形眼镜可能会减缓儿童近视的进展。本研究的目的是确定角膜塑形隐形眼镜是否会减缓眼球生长。
40名受试者佩戴角膜塑形隐形眼镜。所有受试者年龄在8至11岁之间，近视度数在-0.75 D至-4.00 D之间，散光小于1.00 D。受试者与另一项近视对照研究中的软性隐形眼镜佩戴者年龄匹配。在基线时和之后的2年中每年进行A超检查。
40名受试者中有28名（70%）佩戴角膜塑形隐形眼镜2年。两组在基线时的屈光不正和眼轴长度相似。角膜塑形组的眼轴长度年变化率明显低于软性隐形眼镜佩戴者（年变化平均差异=0.16 mm，p=0.0004）。玻璃体腔深度也有类似变化（年变化平均差异=0.10 mm，p=0.006）。
结果证实了先前关于佩戴角膜塑形隐形眼镜后眼球生长减缓的报道。
