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迈向基于皮层的视觉神经假体的发展。

Toward the development of a cortically based visual neuroprosthesis.

作者信息

Normann Richard A, Greger Bradley, House Paul, Romero Samuel F, Pelayo Francisco, Fernandez Eduardo

机构信息

Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA.

出版信息

J Neural Eng. 2009 Jun;6(3):035001. doi: 10.1088/1741-2560/6/3/035001. Epub 2009 May 20.

DOI:10.1088/1741-2560/6/3/035001
PMID:19458403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2941645/
Abstract

Motivated by the success of cochlear implants for deaf patients, we are now facing the goal of creating a visual neuroprosthesis designed to interface with the occipital cortex as a means through which a limited but useful sense of vision could be restored in profoundly blind patients. We review the most important challenges regarding this neuroprosthetic approach and emphasize the need for basic human psychophysical research on the best way of presenting complex stimulating patterns through multiple microelectrodes. Continued research will hopefully lead to the development of and design specifications for the first generation of a cortically based visual prosthesis system.

摘要

受人工耳蜗在聋人患者中取得成功的启发,我们现在面临着创建一种视觉神经假体的目标,该假体旨在与枕叶皮层连接,以此作为一种手段,使深度失明患者能够恢复有限但有用的视觉。我们回顾了关于这种神经假体方法的最重要挑战,并强调了对通过多个微电极呈现复杂刺激模式的最佳方式进行基础人类心理物理学研究的必要性。持续的研究有望促成第一代基于皮层的视觉假体系统的开发和设计规范。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f8f/2941645/c7bb2db7ee56/nihms-233378-f0008.jpg
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