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癌症患者中微孢子虫的发病率。

Incidence of microsporidia in cancer patients.

作者信息

Lono Angela R, Kumar Suresh, Chye Tan T

机构信息

University of Malaya, Kuala Lumpur, Malaysia.

出版信息

J Gastrointest Cancer. 2008;39(1-4):124-9. doi: 10.1007/s12029-009-9065-z. Epub 2009 May 21.

Abstract

INTRODUCTION

Microsporidia are considered opportunistic pathogens as evidenced by the significant detection in immunocompromised HIV/AIDS population. Cancer patients receiving chemotherapy are considered to be immunosuppressed.

MATERIALS AND METHODS

Stool samples were collected from 311 cancer patients in the Klang Valley. Each sample underwent water-ether concentration and staining with modified trichrome stain.

RESULTS AND DISCUSSION

Sixty-eight samples were positive by oil immersion examination. Polymerase chain reaction amplification with specific primers on those samples amplified Encephalitozoon intestinalis from two of the samples and Encephalitozoon hellem from one sample.

摘要

引言

微孢子虫被认为是机会性病原体,这在免疫功能低下的艾滋病毒/艾滋病患者群体中的大量检出得到了证实。接受化疗的癌症患者被认为处于免疫抑制状态。

材料与方法

从巴生谷的311名癌症患者中采集粪便样本。每个样本进行水-乙醚浓缩,并使用改良三色染色法染色。

结果与讨论

通过油镜检查,68个样本呈阳性。对这些样本使用特异性引物进行聚合酶链反应扩增,从两个样本中扩增出肠脑炎微孢子虫,从一个样本中扩增出海伦脑炎微孢子虫。

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