Yap Angela Frances, Kwan Yu Heng, Tan Chuen Seng, Ibrahim Syed, Ang Seng Bin
Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Department of Pharmacy, Khoo Teck Puat Hospital, Singapore, Singapore.
BMC Complement Altern Med. 2017 Jun 14;17(1):311. doi: 10.1186/s12906-017-1825-x.
Quality of life has become an important aspect in the measurement of the health of an individual as the population ages. Rhythm-centred music making (RMM) has been shown to improve physical, psychological and social health. The purpose of this study was to explore the effects of RMM on quality of life, depressive mood, sleep quality and social isolation in the elderly.
A randomised controlled trial with cross over was conducted. 54 participants were recruited with 27 participants in each arm. In phase 1, group A underwent the intervention with group B as the control. In phase 2, group B underwent the intervention with group A as the control. The intervention involved 10 weekly RMM sessions. Patient related outcome data which included European Quality of Life-5 Dimensions (EQ5D), Geriatric Depression Scale (GDS), Pittsburg Sleep Quality Index (PSQI) and Lubben Social Network Scale (LSNS) scores were collected before the intervention, at 11th and at the 22nd week.
A total of 31 participants were analyzed at the end of the study. The mean age was 74.65 ± 6.40 years. In analysing the change in patient related outcome variables as a continuous measure, participation in RMM resulted in a non-significant reduction in EQ5D by 0.004 (95% CI: -0.097,0.105), GDS score by 0.479 (95% CI:-0.329,1.287), PSQI score by 0.929 (95% CI:- 0.523,2.381) and an improvement in LSNS by 1.125 (95% CI:-2.381,0.523). In binary analysis, participation in RMM resulted in a 37% (OR = 1.370, 95% CI: 0.355,5.290), 55.3% (OR = 1.553, 95% CI: 0.438,5.501), 124.1% (OR = 2.241, 95% CI = 0.677,7.419) and 14.5% (OR = 1.145, 95% CI = 0.331,3.963) non-significant increase in odds of improvement in EQ5D, GDS, PSQI and LSNS scores respectively.
Participation in RMM did not show any statistically significant difference in the quality of life of the participants. It is however, an interesting alternative tool to use in the field of integrative medicine. Moving forward, a larger study could be performed to investigate the effects of RMM on the elderly with an inclusion of a qualitative component to evaluate effects of RMM that were not captured by quantitative indicators.
This trial was retrospectively registered. This trial was registered in the Australian New Zealand Clinical Trials Registry under trial number ACTRN12616001281482 on 12 September 2016.
随着人口老龄化，生活质量已成为衡量个体健康状况的一个重要方面。以节奏为中心的音乐创作（RMM）已被证明能改善身体、心理和社会健康。本研究的目的是探讨RMM对老年人生活质量、抑郁情绪、睡眠质量和社会隔离的影响。
进行了一项交叉随机对照试验。招募了54名参与者，每组27人。在第1阶段，A组接受干预，B组作为对照。在第2阶段，B组接受干预，A组作为对照。干预包括每周10次RMM课程。在干预前、第11周和第22周收集患者相关结局数据，包括欧洲五维健康量表（EQ5D）、老年抑郁量表（GDS）、匹兹堡睡眠质量指数（PSQI）和鲁本社会网络量表（LSNS）得分。
研究结束时共分析了31名参与者。平均年龄为74.65±6.40岁。在将患者相关结局变量的变化作为连续测量指标进行分析时，参与RMM导致EQ5D非显著降低0.004（95%CI：-0.097，0.10），GDS得分降低0.479（95%CI：-0.329，1.287），PSQI得分降低0.929（95%CI：-0.523，2.381），LSNS得分提高1.125（95%CI：-2.381，0.523）。在二元分析中，参与RMM导致EQ5D、GDS、PSQI和LSNS得分改善的几率分别非显著增加37%（OR=1.370，95%CI：0.355，5.290）、55.3%（OR=1.553，95%CI：0.438，5.501）、124.1%（OR=2.241，95%CI=0.677，7.419）和14.5%（OR=1.145，95%CI=0.331，3.963）。
参与RMM在参与者的生活质量方面未显示出任何统计学上的显著差异。然而，它是综合医学领域中一种有趣的替代工具。展望未来，可以进行更大规模的研究来调查RMM对老年人的影响，并纳入定性成分以评估定量指标未捕捉到的RMM的影响。
本试验为回顾性注册。该试验于2016年9月12日在澳大利亚新西兰临床试验注册中心注册，注册号为ACTRN12616001281482。
