Elinder C G, Ahrengart L, Lidums V, Pettersson E, Sjögren B
Department of Renal Medicine, Huddinge University Hospital, Karolinska institutet, Sweden.
Br J Ind Med. 1991 Nov;48(11):735-8. doi: 10.1136/oem.48.11.735.
Using atomic absorption spectrometry the aluminium concentrations in blood and urine and in two iliac bone biopsies obtained from welders with long term exposure to fumes containing aluminium were measured. The urinary excretion of two workers who had welded for 20 and 21 years varied between 107 and 351 micrograms Al/l, more than 10 times the concentration found in persons without occupational exposure. Urinary aluminium excretion remained high many years after stopping exposure. Blood and bone aluminium concentrations (4-53 micrograms Al/l and 18-29 micrograms Al/g respectively) were also raised but not to the same extent as urine excretion. It is concluded that long term exposure to aluminium by inhalation gives rise to accumulation of aluminium in the body and skeleton of health persons, and that the elimination of retained aluminium is very slow, in the order of several years.
采用原子吸收光谱法，对长期接触含铝烟雾的焊工的血液、尿液以及两块髂骨活检样本中的铝浓度进行了测定。两名分别从事焊接工作20年和21年的工人，其尿铝排泄量在107至351微克铝/升之间变化，比未接触职业性铝的人群中发现的浓度高出10倍以上。停止接触多年后，尿铝排泄量仍居高不下。血液和骨骼中的铝浓度（分别为4 - 53微克铝/升和18 - 29微克铝/克）也有所升高，但程度不及尿铝排泄量。得出的结论是，长期吸入铝会导致健康人的身体和骨骼中铝的蓄积，并且体内留存铝的消除非常缓慢，大约需要数年时间。
