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接触铝粉的工人血液和尿液中的铝浓度。

Blood and urine concentrations of aluminium among workers exposed to aluminium flake powders.

作者信息

Ljunggren K G, Lidums V, Sjögren B

机构信息

Industrial Health Centre (Hälsocentralen), Jönköping, Sweden.

出版信息

Br J Ind Med. 1991 Feb;48(2):106-9. doi: 10.1136/oem.48.2.106.

DOI:10.1136/oem.48.2.106
PMID:1998604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1035329/
Abstract

In a group of workers exposed to aluminium flake powders, blood and urine concentrations of aluminium were assessed before and after vacation. Another group was investigated after retirement. Workers currently exposed to aluminium flake powders had urinary concentrations of the metal 80-90 times higher than those in occupationally non-exposed referents. The calculated half life for concentrations of aluminium in urine was five to six weeks based on four to five weeks of non-exposure. Among the retired workers the half lives varied from less than one up to eight years and were related to the number of years since retirement. These results indicate that aluminium is retained and stored in several compartments of the body and eliminated from these compartments at different rates.

摘要

在一组接触铝粉的工人中,在休假前后对其血液和尿液中的铝浓度进行了评估。另一组在退休后接受了调查。目前接触铝粉的工人尿液中该金属的浓度比职业未接触对照者高80至90倍。根据四至五周的无接触情况计算,尿液中铝浓度的半衰期为五至六周。在退休工人中,半衰期从不到一年到八年不等,且与退休后的年数有关。这些结果表明,铝在体内的多个隔室中潴留和储存,并以不同速率从这些隔室中排出。

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本文引用的文献

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Pulmonary fibrosis and encephalopathy associated with the inhalation of aluminium dust.与吸入铝尘相关的肺纤维化和脑病。
Br J Ind Med. 1962 Oct;19(4):253-63. doi: 10.1136/oem.19.4.253.
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Evaluation of some critical factors affecting determination of aluminum in blood, plasma, or serum by electrothermal atomic absorption spectroscopy.电热原子吸收光谱法测定血液、血浆或血清中铝时某些关键影响因素的评估。
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Dialysis encephalopathy and aluminum exposure: an epidemiologic analysis.透析性脑病与铝暴露:一项流行病学分析。
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Aluminium in the blood and urine of industrially exposed workers.从事工业生产的工人血液和尿液中的铝含量。
Br J Ind Med. 1983 Aug;40(3):301-4. doi: 10.1136/oem.40.3.301.
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Exposure and urinary excretion of aluminum during welding.焊接过程中铝的暴露与尿排泄
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Uptake and urinary excretion of aluminum among welders.焊工体内铝的摄取与尿排泄情况
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Elevated aluminum persists in serum and tissues of rabbits after a six-hour infusion.在六小时的输注后,兔血清和组织中的铝含量持续升高。
Toxicol Appl Pharmacol. 1989 Jun 1;99(1):133-8. doi: 10.1016/0041-008x(89)90118-x.
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New evidence for an active role of aluminum in Alzheimer's disease.铝在阿尔茨海默病中起积极作用的新证据。
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