芦荟与磺胺嘧啶银乳膏治疗二度烧伤的随机对照研究。
Aloe versus silver sulfadiazine creams for second-degree burns: a randomized controlled study.
作者信息
Khorasani Ghasemali, Hosseinimehr Seyed Jalal, Azadbakht Mohammad, Zamani Arman, Mahdavi Mohammad Reza
机构信息
Department of Surgery, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
出版信息
Surg Today. 2009;39(7):587-91. doi: 10.1007/s00595-008-3944-y. Epub 2009 Jun 28.
PURPOSE
Burn injury is associated with a high incidence of death and disability; yet its management remains problematic and costly. We conducted this clinical study to evaluate the efficacy of aloe vera cream for partial thickness burn wounds and compare its results with those of silver sulfadiazine (SSD).
METHODS
Thirty patients with similar types of second-degree burns at two sites on different parts of the body were included in this study. Each patient had one burn treated with topical SSD and one treated with aloe cream, randomly.
RESULTS
The rate of re-epithelialization and healing of the partial thickness burns was significantly faster in the site treated with aloe than in the site treated with SSD (15.9 +/- 2 vs 18.73 +/- 2.65 days, respectively; P < 0.0001). The sites treated with aloe were completely healed in less than 16 days vs 19 days for the sites treated with SSD.
CONCLUSION
These results clearly demonstrated the greater efficacy of aloe cream over SSD cream for treating second-degree burns.
目的
烧伤与高死亡率和残疾率相关；然而其治疗仍然存在问题且成本高昂。我们开展这项临床研究以评估芦荟霜对浅二度烧伤创面的疗效，并将其结果与磺胺嘧啶银（SSD）的结果进行比较。
方法
本研究纳入了30例在身体不同部位的两个部位有相似类型二度烧伤的患者。每位患者的一处烧伤采用外用SSD治疗，另一处烧伤随机采用芦荟霜治疗。
结果
浅二度烧伤的再上皮化和愈合速度在使用芦荟治疗的部位明显快于使用SSD治疗的部位（分别为15.9±2天和18.73±2.65天；P<0.0001）。使用芦荟治疗的部位在不到16天内完全愈合，而使用SSD治疗的部位则为19天。
结论
这些结果清楚地表明，芦荟霜在治疗二度烧伤方面比SSD霜具有更高的疗效。
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