用纤维蛋白特异性锰纳米胶体灵敏且高效地检测血栓。
Sensitive and efficient detection of thrombus with fibrin-specific manganese nanocolloids.
作者信息
Pan Dipanjan, Senpan Angana, Caruthers Shelton D, Williams Todd A, Scott Mike J, Gaffney Patrick J, Wickline Samuel A, Lanza Gregory M
机构信息
Division of Cardiology and C-TRAIN, Washington University School of Medicine, St. Louis, MO 63108, USA.
出版信息
Chem Commun (Camb). 2009 Jun 14(22):3234-6. doi: 10.1039/b902875g. Epub 2009 Apr 22.
Abstract
In this work, we report novel fibrin targeted "soft-type" manganese-based contrast agents for MRI with the potential to noninvasively image intravascular thrombus which could warrant aggressive medical intervention to preclude subsequent myocardial infarction or stroke.
摘要
在本研究中，我们报告了用于磁共振成像（MRI）的新型纤维蛋白靶向“软型”锰基造影剂，其具有对血管内血栓进行无创成像的潜力，这可能有助于采取积极的医学干预措施以预防后续的心肌梗死或中风。
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2
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3
MR tracking of transplanted cells with "positive contrast" using manganese oxide nanoparticles.
Magn Reson Med. 2008 Jul;60(1):1-7. doi: 10.1002/mrm.21622.
4
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Angew Chem Int Ed Engl. 2008;47(26):4918-21. doi: 10.1002/anie.200800563.
5
Gadolinium-enhanced magnetic resonance imaging, renal failure and nephrogenic systemic fibrosis/nephrogenic fibrosing dermopathy.
Curr Med Chem. 2008;15(12):1229-35. doi: 10.2174/092986708784310396.
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J Am Coll Radiol. 2008 Jan;5(1):45-52. doi: 10.1016/j.jacr.2007.08.018.
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10
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