脊髓灰质炎病毒的形态发生。IV. 沉降系数为150S且具有前病毒特性的颗粒的存在
Morphogenesis of poliovirus. IV. existence of particles sedimenting at 150S and having the properties of provirion.
作者信息
Guttman N, Baltimore D
出版信息
J Virol. 1977 Aug;23(2):363-7. doi: 10.1128/JVI.23.2.363-367.1977.
Abstract
An apparent precursor to the poliovirion that cosediments with the virion at 150S was identified by its content of VP-0. It has properties previously associated with the provirion, a structure that sedimented at 125S, and it may be an alternate form of provirion. Like virions, the 150S precursor binds to and elutes from cells, after which it sediments at about 125S.
摘要
一种明显的脊髓灰质炎病毒体前体在150S时与病毒体共同沉降，通过其VP-0含量得以鉴定。它具有先前与前病毒体相关的特性，前病毒体是一种在125S时沉降的结构，它可能是前病毒体的一种替代形式。与病毒体一样，150S前体与细胞结合并从细胞中洗脱，之后它在约125S时沉降。
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