Scott Phillip
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Cell Host Microbe. 2009 Jul 23;6(1):3-4. doi: 10.1016/j.chom.2009.07.002.
Leishmaniasis is a chronic infection in which intracellular parasites avoid destruction by the immune system. Using intravital imaging, Filipe-Santos et al. (2009) demonstrate that some parasitized dendritic cells receive much less attention than others during their choreographed dance with T cells, suggesting that these "wallflowers" could allow for parasite survival.
利什曼病是一种慢性感染,其中细胞内寄生虫可避免被免疫系统破坏。菲利佩 - 桑托斯等人(2009年)利用活体成像技术证明,在与T细胞精心编排的“舞蹈”过程中,一些被寄生的树突状细胞受到的关注远少于其他细胞,这表明这些“壁花”可能会使寄生虫得以存活。