Li Yena, Yang Shangjun, Bai Shaoyan
Institute of Materia Medica, Shandong Academy of Medical Sciences, Ji'nan 250062, China.
Zhongguo Zhong Yao Za Zhi. 2009 Apr;34(7):854-7.
To investigate the chemical constituents of the roots of Angelica polymorpha.
Silica gel column chromatography was employed for the isolation and purification of chemical constituents. The structures were identified on the basis of spectral data and chemical evidence.
Fourteen compounds were isolated and identified as follows, 5-hydroxy-2-[(angeloyloxy) methyl] furan [3', 2': 6, 7] chromone (1), octacosanoic acid (2), isoimperatorin (3), 3'S-(-)-O-acetylhamaudol (4), bergapten (5), iso-oxypeucedanin (6), beta-sitosterol (7), angeliticin A (8) , saxalin (9), pabulenol (10), noreugenin (11), oxypeucedanin hydrate (12), daucosterol (13), sucrose (14).
Compound 1 is a new chromone, named polymorchromone A. Compounds 2, 4, 11, 13, 14 were isolated from A. polymorpha for the first time.
研究多形当归根的化学成分。
采用硅胶柱色谱法对化学成分进行分离纯化。根据光谱数据和化学证据鉴定结构。
分离并鉴定出14个化合物，分别为5-羟基-2-[(当归酰氧基)甲基]呋喃[3',2':6,7]色原酮(1)、二十八烷酸(2)、异欧前胡素(3)、3'S-(-)-O-乙酰哈马豆醇(4)、补骨脂素(5)、异氧化前胡素(6)、β-谷甾醇(7)、当归苷A(8)、沙杏苷(9)、帕布勒醇(10)、去甲欧芹属素乙(11)、氧化前胡素水合物(12)、胡萝卜苷(13)、蔗糖(14)。
化合物1是一个新的色原酮，命名为多形色原酮A。化合物2、4、11、13、14首次从多形当归中分离得到。
